Hae Kyung Im and her co-authors has published the PrediXcan method in Nature Genetics (August 10th, 2015)
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3367.html
• HS Rats Pilot Projects 2016
Pilot Studies in HS Outbred Rats Supporting Drug Abuse Research Center of Excellence The NIDA center for GWAS in outbred rats (P50DA037844) focuses on quantitative genetic studies of a range of psychologically complex drug abuse-related phenotypes in outbred rats. In order to broaden the impact of this center and to promote rat genetics studies we … Read more…
• 4th Brain Awareness Day, October 24, 2015
4th Brain Awareness Day gathered 100+ high school students, teachers and other guests. Brain Awareness Day was supported in part by NIDA Center for GWAS in Outbred Rats. Oksana Polesskaya, PhD., Scientific Coordinator, presented overview of Center’s research. Nicholas Grahame, Ph.D., Eva E. Redei, Ph.D., and Erik Jorgensen, Ph.D. delivered lectures on topics related to brain … Read more…
• 2nd Annual Retreat for the Center took place October 16-17.
Twenty three Center members and 10 Advisory Board members came to Chicago to hear reports and discuss progress and future directions. Visit meeting page for details.
• IMGC2015 – registration is open
Registration and abstract submission for the 29th International Mammalian Genome Conference IMGC2015 that will be held from November 8th to November 11th, 2015 in Yokohama, Japan are now open. See more at http://www.imgc2015.jp/registration.html
• MCW Gene Editing Rat Resource Center is pleased to announce that the 4th round of applications for gene nominations for genetically modified rats are now being accepted!
The National Heart, Lung, and Blood Institute (NHLBI) has awarded the Medical College of Wisconsin an R24 Resource grant to make ~200 genetically modified rat strains over the next five years. These models will be of interest and value to the mission of the NHLBI. The NHLBI promotes the prevention and treatment of heart, lung, and blood diseases through scientific discovery directed toward the causes of disease and translation of basic discoveries into clinical practice.
Round 4 Deadline: April 12, 2015 (Midnight Milwaukee, WI time). Submit completed application to: [email protected].
More information: http://rgd.mcw.edu/wg/gerrc
• GWAS can be now performed under FOA “The Identification of Gene Variants for Addiction Related Traits by Next-Gen Sequencing in Model Organisms Selectively Bred for Addiction Traits”
The U01 replaces the UH2/UH3 so it has more flexibility and GWAS can now be performed.
“The Identification of Gene Variants for Addiction Related Traits by Next-Gen Sequencing in Model Organisms Selectively Bred for Addiction Traits (UH2/UH3)” FOA and Notice of Change are now published. Please see the links below:
http://grants.nih.gov/grants/guide/notice-files/NOT-DA-15-042.html
2014 Pilot Grants awarded
Congratulations to the 2014 Pilot Grants recipients:
Dr. Xiaoxi Zhuang, University of Chicago. “GWAS of nicotine-induced behavioral sensitization in Drosophila”
Drs. Nancy Cox and Hae Kyung Im, University of Chicago. “Applying PrediXcan to Genes implicated in Rat Neurobehavioral Studies”
Dr. Martin Sarter, University of Michigan. “CHT regression as a Neuromarker of Sign-Tracking”
Dr. Paul Meyer, University at Buffalo. “The effects of cadherin-13 gene deletion on addiction-like behaviors”
NIDA researchers confirm important brain reward pathway
NIH study in rodents identifies a pathway that starts with glutamate and ends with activation of dopamine reward system Details of the role of glutamate, the brain’s excitatory chemical, in a drug reward pathway have been identified for the first time. This discovery in rodents — published today in Nature Communications — shows that stimulation … Read more…