Journal Club – Rat Genes

In 2024 we will have monthly HS rats meetings; information is posted on the Meetings page.

In 2019 we joined Journal Club with the Center for Systems Neurogenetics of Addiction (P50DA039841), led by Dr. Elissa Chesler, Jackson Laboratory (link).

To join:
Join WebEx meeting
Meeting number (access code): 731 976 718

Join by phone
+1-240-454-0887 United States Toll (San Jose)

26. September 18, 2019, Wednesday, 10 am PST (1 pm EST)

25. August 14, 2019, Wednesday, 11 am PST (2 pm EST)

24. July 17, 2019, Wednesday, 11 am PST (2 pm EST)

23. June 19, 2019, Wednesday, 11 am PST (2 pm EST)

22. May 15, 2019, Wednesday, 10 am PST (1 pm EST)

21. April 17, 2019, Wednesday, 10 am PST (1 pm EST)

20. March 2o, 2019, Wednesday, 10 am PST (1 pm EST)

Article: Pascoli et al., Stochastic synaptic plasticity underlying compulsion in a model of addiction. Nature 2018.

19. February 20, 2019, Wednesday, 10 am PST (1 pm EST)

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To join P50 on-line meeting, go to https://uchealth.zoom.us/j/986773198

call in (646) 876 9923, Meeting ID: 986 773 198.

18. December 5, 2018, Wednesday, 12 pm PST

Presenter: Hailley Pearson, graduate student, Meyer lab

Article: Venniro et al., Volitional social interaction prevents drug addiction in rat models. Nature Neuroscience, 2018

17. March 13, 2017, Monday, 11 am PST

Presenter: Jerry Richards

Title: Delay Discounting phenotype in HS rats.

16. January 9, 2017 Monday, 11 am PST

Presenter: Abraham Palmer

Article: Parker et al., Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nature Genetics, 2016.

15. December 12, 2016, Monday, 11 am PST

Presenter: Yu-Yu Ren, Palmer Lab

Article: Puckett EE et al., Global population divergence and admixture of the brown rat (Rattus norvegicus). Proc Biol Sci. 2016

14. October 10, 2016, Monday, 11 am PST

Presenter: Hao Chen Lab

Article: Wang et al. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. Elife. 2016

Presentation slides

13. June 22, 2016, Wed, 10 am PST

Presenter: Tony George (Graduate student and Research Technician, Richards Lab)

Article: Neidl R et al. Late-life environmental enrichment induces acetylation events and NFkB-dependent regulation in the hippocampus of aged rats showing improved plasticity and learning. J Neurosci 2016.

12. May 23, 2016, Monday, 12 pm PST

Presenter: Greg Loney (Meyer Lab)

Article: Yazdani N, et al. Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity. PLoS Genet. 2015.

11. April 25, 2016, Monday, 9 am PST

Presenter: Alex Gileta (graduate student, Palmer lab)

Article: Dickson PE, Miller MM, Calton MA, Bubier JA, Cook MN, Goldowitz D, Chesler EJ, Mittleman G. Systems genetics of intravenous cocaine self-administration in the BXD recombinant inbred mouse panel. Psychopharmacology. 2015. PMID: 26581503.

Presentation slides

10. March 11, 2016, Friday, 10 am PST

Dr. Terry Robinson will discuss the animal models of addiction as studying addiction-related traits rather than “addiction”. Terry will discuss behavioral pharmacology related to animal models of addiction. He will explain why, in his view, most of what is going on in the field may be leading us astray – and will present a promising model which his lab develops.

Articles:

How fast and how often: The pharmacokinetics of drug use are decisive in addiction. llain F, Minogianis EA, Roberts DC, Samaha AN. Neurosci Biobehav Rev.
2015 Review. PMID: 26116543
The motivation to self-administer is increased after a history of spiking brain levels of cocaine. Zimmer BA, Oleson EB, Roberts DC. Neuropsychopharmacology. 2012 PMID: 22453139

9. January 29, 2016, Friday, 10 am PST

Presenter: Ignacio (Nacho) Rivero-Covelo (Postdoctoral Research Fellow, Flagel lab)

Article: Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood. Golubeva AV, Crampton S, Desbonnet L, Edge D, O’Sullivan O, Lomasney KW, Zhdanov AV, Crispie F, Moloney RD, Borre YE, Cotter PD, Hyland NP, O’Halloran KD, Dinan TG, O’Keeffe GW, Cryan JF. Psychoneuroendocrinology. 2015 PMID: 26135201