• MCW Gene Editing Rat Resource Center is pleased to announce that the 4th round of applications for gene nominations for genetically modified rats are now being accepted!

The National Heart, Lung, and Blood Institute (NHLBI) has awarded the Medical College of Wisconsin an R24 Resource grant to make ~200 genetically modified rat strains over the next five years. These models will be of interest and value to the mission of the NHLBI. The NHLBI promotes the prevention and treatment of heart, lung, and blood diseases through scientific discovery directed toward the causes of disease and translation of basic discoveries into clinical practice.

Round 4 Deadline: April 12, 2015 (Midnight Milwaukee, WI time). Submit completed application to: mcwcustomrats@mcw.edu.

More information: http://rgd.mcw.edu/wg/gerrc

• GWAS can be now performed under FOA “The Identification of Gene Variants for Addiction Related Traits by Next-Gen Sequencing in Model Organisms Selectively Bred for Addiction Traits”

The U01 replaces the UH2/UH3 so it has more flexibility and GWAS can now be performed.

“The Identification of Gene Variants for Addiction Related Traits by Next-Gen Sequencing in Model Organisms Selectively Bred for Addiction Traits (UH2/UH3)” FOA and Notice of Change are now published. Please see the links below:

http://grants.nih.gov/grants/guide/notice-files/NOT-DA-15-042.html

http://grants.nih.gov/grants/guide/pa-files/PAR-15-120.html

2014 Pilot Grants awarded

Congratulations to the 2014 Pilot Grants recipients:

Dr. Xiaoxi Zhuang, University of Chicago. “GWAS of nicotine-induced behavioral sensitization in Drosophila”

Drs. Nancy Cox and Hae Kyung Im, University of Chicago. “Applying PrediXcan to Genes implicated in Rat Neurobehavioral Studies”

Dr. Martin Sarter, University of Michigan. “CHT regression as a Neuromarker of Sign-Tracking”

Dr. Paul Meyer, University at Buffalo. “The effects of cadherin-13 gene deletion on addiction-like behaviors”

Pilot Project Grants Submitted

Seven pilot project grant proposals for research projects connected to the NIDA Center for GWAS in Rats were submitted in response to the initial call for submissions. They span a wide range of research disciplines from fruit fly genetics to bioinformatics, each is intended to enhance the impact of the center. The principal investigator of … Read more…

The 2015 International Workshop on Statistical Genetic Methods for Human Complex Traits

A workshop on advanced methods in statistical genetics will be held in Boulder, Colorado, March 2nd to 6th, 2015. This workshop is intended for advanced students of statistical genetics who are interested in genome-wide association studies (GWAS). The local host is Dr. John K. Hewitt, Institute for Behavioral Genetics, University of Colorado. Dr. Benjamin Neale, … Read more…