New rat genome assembly mRatNor1 is finished and available

You can find the mRatNor1.1 assembly at ftp://ftp.sanger.ac.uk/pub/users/kj2/Darwin. The files are: mRatNor1_1.curated_primary.20200424.facontaining the primary assembly. The scaffold names need to be translated using  mRatNor1_1.chromosome.list.csvwhere the entries refer to <scaffold_name>,<chr_name>,<yes if it’s the main part of the chromosome/no if it’s an unlocalised part of the chromosome>  mRatNor1_1.all_haplotigs.20200424.faContains the alternative assembly. CAVEAT: This is the current assembly not … Read more…

2020 pilot grants awarded

Congratulations to the 2020 Pilot Grants recipients: Francesca Telese, PhD (University of California – San Diego).Project: “Creating the dataset for TWAS in HS rats”. Paul Meyer, PhD (University at Buffalo).Project: “Genetic substrates of heroin’s motivational effects”. Giordano DeGuglielmo, PhD (University of California – San Diego).Project: “Characterization of addiction-like behaviors in alcohol-dependent rats”. Olivia Osborn, PhD (University of California – … Read more…

Updates related to COVID19

COVID-19 pandemic affected projects and programs performed by this Center as follows: 1) The Research Projects 1-3 have been temporarily shut down, because phenotyping work is not conducive to social distancing.2) The Research Project 4 is ongoing; bioinformaticians are working from homes. 3) The HS rats colony (Breeding Core) is being maintained/preserved, and expected to … Read more…