The NIDA center for GWAS in outbred rats (P50DA037844) focuses on quantitative genetic studies of a range of psychologically complex drug abuse-related phenotypes in rats. In order to broaden the impact of this center we will support pilot projects that are related to the center’s objectives. Applications are accepted from Assistant, Associate and full Professors (or equivalent rank) at any of the participating institutions (UCSD, UofM, RIA/SUNY Buffalo, UTHSC, and Wake Forest University ). Junior investigators are especially encouraged to apply. For example, we envision proposals that would:
- Propose additional behavioral, neuroanatomical, neurochemical, proteomic, etc. phenotyping in rats already being tested by the center (contact the relevant parties at your institution)
- Propose to obtain additional rats from the breeding core to explore other drug-abuse relevant phenotypic domains.
- Utilize the services of the genotyping and sequencing core to perform genotype-by-sequencing analysis of drug-abuse relevant quantitative traits
- Develop tools to integrate genetic studies in rats with other analogous studies in other organisms (e.g. fly, human)
If you have questions please contact Pilot Core Director (Oksana Polesskaya, PhD).