The journal GENETICS highlights articles on the study of multiparental populations in its current issue. As the limitations of two-parent cross designs have become obvious, geneticists are struggling with analysis of experimental populations that have more than two segregating alleles. The articles in the MPP collection, along with their data and transparent methods, should stimulate discussion and, hopefully, move the field forward. The NIDA center for GWAS in outbred rats relies heavily on the type of experiments and analyses described in the special issue of GENETICS. This issue can be found here.
