We use color coding to visually represent the genetic contributions of each founder strain in N/NIH heterogeneous stock (HS) rats. This method helps track the inheritance and distribution of alleles from the original strains throughout the HS population, providing clarity in genetic analysis. Each founder strain is assigned a distinct color to simplify genetic mapping. … Read more…
Congratulations to the 2025 Pilot Grants recipients: Caitlin A. Orsini, PhD (University of Texas at Austin).Project: Examination of behavioral vulnerability factors that confer risk to synthetic opioid use.
The manuscript titled “RatXcan: A framework for cross-species integration of genome-wide association and gene expression data” was accepted in PLOS Genetics.
Authors: Natasha Santhanam, Sandra Sanchez-Roige, Sabrina Mi, Yanyu Liang, Apurva S. Chitre, Daniel Munro, Denghui Chen, Riyan Cheng, Festus Nyasimi, Jianjun Gao, Anthony M. George, Alexander F. Gileta, Wenyan Han, Katie Holl, Alesa Hughson, Christopher P. King, Alexander C. Lamparelli, Connor D. Martin, Angel Garcia-Martinez, Celine L. St. Pierre, Sarah Sumner, Jordan Tripi, Tengfei Wang, Hao Chen, Shelly Flagel, Keita Ishiwari, Paul Meyer, Oksana Polesskaya, Laura Saba, Leah C. Solberg Woods, Abraham A. Palmer, Hae Kyung Im.
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The manuscript titled “Distinct Behavioral Profiles and Neuronal Correlates of Heroin Vulnerability Versus Resiliency in a Multi-Symptomatic Model of Heroin Use Disorder in Rats” was published in the American Journal of Psychiatry.
Authors: Brittany N. Kuhn, Nazzareno Cannella, Ayteria D. Crow, Veronica Lunerti, Arkobrato Gupta, Stephen J. Walterhouse, Carter Allen, Reda M. Chalhoub, Eric Dereschewitz, Analyse T. Roberts, Mackenzie Cockerham, Angela Beeson, Rusty W. Nall, Abraham A. Palmer, Gary Hardiman, Leah C. Solberg Woods, Dongjun Chung, Roberto Ciccocioppo, Peter W. Kalivas
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The manuscript titled “Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats” was accepted in Molecular Psychiatry.
Authors: Brittany N. Kuhn, Nazzareno Cannella, Apurva S. Chitre, Khai-Minh H. Nguyen, Katarina Cohen, Denghui Chen, Beverly Peng, Kendra S. Ziegler, Bonnie Lin, Benjamin B. Johnson, Thiago Missfeldt Sanches, Ayteria D. Crow, Veronica Lunerti, Arkobrato Gupta, Eric Dereschewitz, Laura Soverchia, Jordan L. Hopkins, Analyse T. Roberts, Massimo Ubaldi, Sarah Abdulmalek, Analia Kinen, Gary Hardiman, Dongjun Chung, Oksana Polesskaya, Leah C. Solberg Woods, Roberto Ciccocioppo, Peter W. Kalivas, and Abraham A. Palmer
Congratulations!